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ProKlenz ONE Alkaline Detergent

ProKlenz® ONE High Performance Alkaline Cleaner

NaOH-based Detergent; Biodegradable Ingredients; Disinfectant and Virucide

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Product Overview

ProKlenz® ONE High Performance Alkaline Cleaner is specially formulated to meet the unique cleaning demands found in the pharmaceutical, biotechnology, cosmetic, dietary supplement, and other industries requiring an effective validatable cleaner.


ProKlenz ONE Detergent is a proprietary blend of sodium hydroxide, an advanced surfactant system and other performance-enhancing ingredients that provide multiple cleaning mechanisms. This low foaming product removes a wide range of process residues, from fermentation by-products to silicone-based emulsions and lubricants, and is ideal for use in CIP, COP and manual applications.

  • Disinfection: ProKlenz ONE Alkaline Detergent is effective against staphylococcus aureus, salmonella enterica, and pseudomonas aeruginosa when used at a 1% concentration of product per gallon of water in 5% blood serum and 250 ppm of hard water at 60°C for a contact time of 5 minutes.
  • Virucidal Activity: ProKlenz ONE alkaline detergent is effective against poliovirus (type 1) when used at a 1% concentration of product per gallon of water in 5% blood serum and 250 ppm of hard water at 60°C for a contact time of 10 minutes.


Productivity - Effective cleaning against a wide variety of pharmaceutical process residues in clean-in-place (CIP), clean-out-of-place (COP), and manual applications
Easy to Validate - Facilitates cleaning validation with a comprehensive support documentation package including specific and non-specific analytical methods, toxicity, and substrate compatibility reports
Efficacy - Delivers microbial control in critical manufacturing processes with disinfectant and virucidal properties (EPA Registration No. 1043-122)
Globally Availability - and manufactured with environmentally friendly ingredients to support harmonization of cleaning processes
Reliability - Manufactured for the pharmaceutical industry in a cGMP compliant, FDA registered and ISO 9001 certified facility



Form - Light yellow to amber 
Odor - None 
Specific Gravity - 77° F (25° C) 1.19, typical 
pH - (1%) 12.5, typical 
Solubility - Complete 
Foam - Low at all temperatures 
Rinsing - Excellent 
Phosphates - None; 0% P 

Certificate of Analysis

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