BSC Biodecontamination with H2O2 Vapor
This article discusses the successful use of hydrogen peroxide vapor in the biodecontamination of Class II Type A2 biological safety cabinets. It will discuss the reasons why this process was chosen, the biodecontamination process and the results.
2019-03-15
Key Takeaways:
- H₂O₂ vapor is non-condensing, compatible with sensitive surfaces and electronics inside biosafety cabinets.
- This EPA-registered method allows easy validation using CIs and BIs, achieving 6-log reduction.
- Vapor penetrates HEPA filters, decontaminating both dirty and clean sides of the cabinet.
- H₂O₂ vapor is less toxic than formaldehyde, leaves no residue and breaks into water and oxygen.
- Proper sealing, vapor distribution and verification ensure safe and effective cabinet release.



