Effective Sterile Powder Transfer for Parenteral Drug Products
This case study examines how Evonik, a leading global contract development and manufacturing organization (CDMO), improved its powder transfer process for parenteral drug products without compromising efficiency or safety.
2022-08-24
Key Takeaways:
- Evonik implemented the AseptiSafe® Bio Valve and STERIS VHP™ 1000ED unit to enable aseptic, high-throughput powder transfer in Grade A (ISO 5) cleanroom.
- The VHP® 1000ED enabled 45-minute validated cycles, allowing near-continuous operation with minimal downtime.
- The split butterfly valve maintained a sterile, sealed connection—preventing particulate release during container changes.
- Mobile, flexible deployment supports cleanrooms with spatial constraints and varying layouts.
- The system complies with EU GMP Annex 1, improving both operational safety and production efficiency.
