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Key Takeaways:

  • Lower life-cycle costs – Cleaning an ultrafiltration membrane with a pharmaceutical detergent rather than NaOH can lengthen membrane life, reducing the need for frequent replacement.  
  • Greater yield – Cleaning with a pharmaceutical detergent enables greater throughput and more productive operation.  
  • Formulated to be free-rinsing, pharmaceutical detergents require less rinse water when cleaning.  
  • Reduced contamination risk – Pharmaceutical detergents are designed to clean more thoroughly, which helps avoid contamination.  
  • Scientific expertise and support – A formulated detergent like STERIS CIP 150™ Alkaline Process & Research Cleaner comes with technical literature and expert support to keep your operation running efficiently.   

Ultrafiltration membranes are a vital component in the biopharmaceutical manufacturing process by enabling the concentration and purification of the necessary harvest material. Routine cleaning of membranes ensures proper function and longer life.

This white paper reviews an experimental study comparing the cleaning performance of a pharmaceutical detergent to sodium hydroxide and concludes that using a formulated detergent offers many advantages.

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