Technical Tip

How to Remove Residue Buildup

Residue has many sources and stubborn residue buildup due to poor cleaning and rinsing practices or chemical incompatibility raises special challenges.
July 1, 2022

Key Takeaways:

  • Residue buildup in cleanrooms often results from poor rinsing, chemical incompatibility or reliance on non-mechanical cleaning methods, and must be addressed with proper cleaning techniques and validated detergents.
  • A 1% v/v solution of ProKlenz™ NpH or ProKlenz™ Booster Sterile Detergent is recommended for effective residue removal, applied using cleanroom techniques and tools like mops, lint-free wipes and sponges.
  • The “pull and lift” technique ensures effective surface coverage, especially when cleaning from cleanest to dirtiest areas, and is critical for minimizing cross-contamination.
  • Stubborn residues may require scrubbing or more aggressive detergents, and aged or damaged surfaces may need special attention to achieve compliant cleanliness. 

Residue has many sources and stubborn residue buildup due to poor cleaning and rinsing practices or chemical incompatibility raises special challenges.

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