Protecting Gloves in Cleanrooms & Critical Environments
Learn how to treat gloves with sterile, double-bagged products to help prevent bacteria and contaminants in cleanrooms and critical environments.
2018-11-08
Key Takeaways:
Personnel are the primary source of contamination in cleanrooms, and routine glove disinfection is essential to maintain aseptic conditions in pharmaceutical, biotech and medical device environments.
Traditional hand sanitizers are not suitable for glove disinfection, as emollients can leave residues that compromise sterility.
STERIS offers four sterile glove treatment solutions—Septihol™ WFI, Septihol Sterile, Septihol Ethyl WFI and 3% Hydrogen Peroxide WFI—each designed for cleanroom compatibility.
These products are sterile, double-bagged and available in various formats, including aerosol, trigger sprayers and gallon bottles.
Using validated glove disinfection products enhances contamination control, reduces risk to product integrity and supports compliance with cleanroom protocols.
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Personnel are typically the primary source of contamination in cleanrooms. This is true at pharmaceutical, biotechnology, cosmetic, nutraceutical and medical device facilities as well as university, government and animal research laboratories.
By routinely treating gloves, personnel can help prevent the transfer of contaminants onto critical surfaces. Here are a few ways to optimize procedures for protecting gloves.
Avoid Glove Contamination to Reduce Cleaning Frequency
It sounds simple, but gloves won’t need to be treated as frequently if they’re not exposed to contaminants. It’s important to have appropriate procedures for material and personnel transfer into cleanroom environments.
Sterile, double-bagged products with minimal particles can easily be transferred into controlled environments and aseptic areas without contaminating gloves.
Create Easy-to-Follow Glove Treatment Protocols
Even when they follow the best cleanroom cleaning procedures and aseptic techniques, personnel who perform critical activities need to protect their gloves to prevent contamination from bacteria.
Treating gloves with the proper agent can help personnel who need to carry out aseptic practices. However, the agent itself is not a replacement for poor aseptic technique. That’s why it’s important to create procedures that are easy to understand and execute.
There are four key variables which affect glove protection. When developing protocols, be specific and include:
How frequently to treat gloves
Proper techniques to apply, agitate and rub the agent onto the gloves
Which agent to use and the proper amount
Criteria for glove replacement
Treat Gloves with the Right Products
Traditional hand sanitizers are not recommended for glove decontamination. That’s because hand sanitizers contain emollients to protect skin, which leave a residue on disposable gloves. To avoid introducing contaminants, it’s important to use sterile products that evaporate quickly and completely so they don’t leave residue on gloves.
The optimal concentration for ethanol and for isopropanol solutions is approximately 70% v/v.
There are many potential sources of residue in aseptic areas, from people to processing equipment. In most situations, residue on floors and walls pose limited risk, hence visually clean is generally the recognized target for a residue management program.
There are many potential sources of residue in aseptic areas, from people to processing equipment. In most situations, residue on floors and walls pose limited risk, hence visually clean is generally the recognized target for a residue management program.
