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VHP 1000ED Biodecontamination Unit

This portable unit uses hydrogen peroxide vapor as a broad-spectrum antimicrobial, and is one of the most versatile pharmaceutical-grade biodecontamination machines for isolators, small enclosures, and cleanrooms.

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Product Overview

STERIS's VHP® 1000ED Biodecontamination Unit provides a safe, environmentally friendly method to decontaminate sealed enclosures up to 10,000ft3.


STERIS's VHP 1000ED Biodecontamination Unit utilizes Vaprox® Hydrogen Peroxide Sterilant (EPA Reg. No. 58779-4) as a means of achieving dry, low temperature sterilization within large sealed enclosures such as cleanrooms and filling lines. The dry, gaseous process consists of four distinct phases:

Dehumidification - Humidity is removed from the room space via an integrated desiccant system. This is done to ensure that a true, dry biodecontamination process is achieved.

Conditioning - Vaprox is rapidly injected by the generator and converted into a dry vapor that quickly raises the level of hydrogen peroxide to an effective concentration.

Biodecontamination - Hydrogen peroxide vapor concentrations are maintained at the target concentration level to provide an effective kill of micro-organisms in the room space.

Aeration - The generator stops injecting Vaprox and accelerates the breakdown of vapor into its environmentally friendly base elements of water vapor and oxygen.

Aeration continues until hydrogen peroxide is reduced to an acceptable level and the room is commissioned for regular use.


  • Productivity - Decontaminates sealed enclosures up to 10,000ft3 such as isolators, small enclosures and rooms.
  • Easy to Validate - GAMP Compliant unit is portable, accurate, reliable, and convenient to use.
  • Flexibility – Mobile unit can be placed inside or outside of the enclosure.
  • Efficacy - The gaseous decontamination process is effective against a wide variety of microorganisms and has a broad range of material compatibility.
  • Green - Provides a non-toxic and environmentally friendly alternative to other decontamination processes. Vaporized Hydrogen Peroxide breaks down to water vapor and Oxygen.

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