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VHP M100 Biodecontamination Unit

An all-in-one hydrogen peroxide vapor generator for pharmaceutical-grade biodecontamination in medical and biological laboratories that’s efficient in closed-loop configurations.

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Product Overview

STERIS's VHP® M100 Biodecontamination Unit provide a flexible, safe, environmentally friendly method of decontamination to small, sealed enclosures.


STERIS's VHP M100 Biodecontamination Unit utilizes Vaprox® Hydrogen Peroxide Sterilant (EPA Reg. No. 58779-4) as a means of achieving dry, low temperature sterilization within sealed enclosures such as isolators and glove boxes. The dry, gaseous process consists of four distinct phases:

Dehumidification - Humidity is removed from the enclosure via an integrated desiccant system. This is done to ensure that a true, dry biodecontamination process is achieved.

Conditioning - Vaprox is rapidly injected by the generator and converted into a dry vapor that quickly raises the level of hydrogen peroxide to an effective concentration.

Biodecontamination - Hydrogen peroxide vapor concentrations are maintained at the target concentration level to provide an effective kill of micro-organisms in the enclosure.

Aeration - The generator stops injecting Vaprox and accelerates the breakdown of vapor into its environmentally friendly base elements of water vapor and oxygen. Aeration continues until hydrogen peroxide is reduced to an acceptable level.


  • Productivity - Provides rapid biodecontamination for small enclosures up to 70ft3.
  • Flexibility - Unit can be mobile or integrated into an isolator or biosafety cabinet.
  • Easy to Validate - GAMP Compliant.
  • Efficacy - The gaseous decontamination process is effective against a wide variety of microorganisms and has a broad range of material compatibility.
  • Green - Provides a non-toxic and environmentally friendly alternative to other decontamination processes. Vaporized Hydrogen Peroxide breaks down to water vapor and Oxygen.


VHP Desiccant Dryer

The VHP Desiccant Dryer is used to regenerate STERIS’s Reusable Desiccant Cartridges, allowing for enclosure dehumidification and the utilization of our VHP technology.

Due to its ease of operation and compact size, the VHP Desiccant Dryer simplifies the biodecontamination process when using STERIS’s VHP M10 and M100 Biodecontamination Units.

  • Intended Use - Regenerating the desiccant filled with 600 g of Reusable Desiccant Cartridges.
  • Fast - 40% shorter cycle time – average time of three hours.
  • Reliable - Continuous operation.
  • Environmentally Friendly - Utilizes reusable desiccants.
  • Controlled - Includes ethernet connectivity for easier troubleshooting.
  • Cabinet Cooling - Ensures longevity of control components.

600 g Reusable Desiccant Cartridge

The 600 g Reusable Desiccant Cartridge is used with the VHP Desiccant Dryer for dehumidification in closed-loop systems.

Certificate of Analysis

Certificates of manufacture/analysis for consumable products by product ID and lot number. (Adobe® Acrobat® Reader required)