Solutions for Materials Transferred into Controlled Environments

November 8, 2018 Article

Cleanrooms provide a contamination-free environment for biotechnology and pharmaceutical testing and manufacturing. However, maintaining a controlled environment is challenging.

The transfer of materials into a cleanroom is one of the primary sources of cleanroom contamination. Keeping the product clean during transfer has several challenges:

  • Not everything going into the cleanroom is sterile
  • Not everything can be steam sterilized for entry
  • Sterilized materials may still need to be cleaned to reduce contamination on packaging

That’s why a material transfer process is key. Setting a cleaning protocol for surfaces, packaging, products, and trolleys during transfer helps control cleanroom contamination.

Just as important as cleanroom cleaning procedures is using the right cleanroom solutions.

Here are several products from STERIS Life Sciences that are proven to be effective solutions in a contamination control strategy for material transfer into cleanroom environments.


Cleanroom Solutions for Transferring Materials into Controlled Environments
Active Ingredient Sporicidal Sterile Packaging Terminally Sterilized Diluted With
Spor-Klenz® Ready-To-Use ETO Sterilant — Yes Yes Yes —
Spor-Klenz® Ready-To-Use Cold Sterilant — Yes No No —
6% Hydrogen Peroxide WFI Sterile Solution 6% Hydrogen Peroxide Possibly Yes No USP WFI
0.525% Hypochlorite WFI Sterile Solution — Possibly Yes No USP WFI
Septihol® WFI Sterile Alcohol Solution 70% Isopropanol No Yes Yes USP WFI
Septihol® Ethyl WFI Sterile Alcohol Solution 62% Ethanol
5% Isopropanol
3% Methanol 		No Yes Yes USP WFI
Septihol® Sterile Alcohol Solution 70% Isopropanol No Yes Yes USP PW

Download 7 Cleanroom Solutions for Transferring Materials to Controlled Environments for more information about maintaining a controlled environment from STERIS Life Sciences.

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